Publications 2011 – present

Zheng, X., and Hunter, T. (2014). Pink1, the first ubiquitin kinase. EMBO J.

Voog, J., Sandall, S. L., Hime, G. R., Resende, L. P. F., Loza-Coll, M., Aslanian, A., Yates II, J. R., Hunter, T., Fuller, M. T., and Jones, D. L. 2014. Escargot restricts niche cell to stem cell conversion in the Drosophila testis. Cell Rep. 7: 722-74.

Brognard, J., and Hunter, T. 2011. Protein kinase signaling networks in cancer. Curr. Opin. Genet. Develop. 21:4-11.

Brognard, J., Zhang, Y.-W., Puto, L. A., and Hunter, T. 2011. Cancer-associated loss-of-function mutations implicate DAPK3 as a tumor-suppressing kinase. Cancer Res. 71:3152-3161.

Chaurushiya, M. S., Lilley, C. E., Aslanian, A., Meisenhelder, J., Scott, D., Landry, S., Ticau, S., Boutell, C., Yates, J. R. III, Schulman, B. A., Hunter, T., and Weitzman, M. D. 2012. Viral E3 ubiquitin ligase-mediated degradation of a cellular E3: viral mimicry of a cellular phosphorylation mark targets the RNF8 FHA domain. Mol. Cell 46:000-000.

Hunter, T. 2012. Why nature chose phosphate to modify proteins. Philos Trans R Soc Lond B Biol Sci 367:2513-2516.

Ma, H., Han, B.K., Guaderrama, M., Aslanian, A., Yates, J.R., 3rd, Hunter, T., and Wittenberg, C. (2014). Psy2 targets the PP4 family phosphatase Pph3 to dephosphorylate Mth1 and repress glucose transporter gene expression. Mol Cell Biol 34:452-463.

Zhu, W., Pao, G.M., Satoh, A., Cummings, G., Monaghan, J.R., Harkins, T.T., Bryant, S.V., Randal Voss, S., Gardiner, D.M., and Hunter, T. (2012). Activation of germline-specific genes is required for limb regeneration in the Mexican axolotl. Dev Biol 370:42-51.

Yang,W., Xia, Y. Hawke, D., Li, X., Liang, J., Aldape, K., Hunter, T., Yung, W.K.A., and Lu, Z.. 2012. PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis. Cell 150:685-696.

Zhang, Q.C., Petrey, D., Deng, L., Qiang. L., Shi, Y., Thu, C. A., Bisikirska, B., Lefebvre, C., Accili, D., Hunter, T., Maniatis, T. Califano, A., and Honig, B. 2012. Structure-based prediction of protein-protein interactions on a genome-wide scale. Nature 490:556-560.

Sun H and Hunter T. 2012. Poly-small ubiquitin-like modifier (PolySUMO)-binding proteins identified through a string search. J Biol Chem. 2012 Dec 7;287(50):42071-83. doi: 10.1074/jbc.M112.410985. Epub 2012 Oct 18.

Zhu W, Kuo D, Nathanson J, Satoh A, Pao GM, Yeo GW, Bryant SV, Voss SR, Gardiner DM and Hunter T. 2012. Retrotransposon long interspersed nucleotide element-1 (LINE-1) is activated during salamander limb regeneration. Dev Growth Differ. 2012 Sep;54(7):673-85. doi: 10.1111/j.1440-169X.2012.01368.x. Epub 2012 Aug 23.

Hunter T. 2012. Why nature chose phosphate to modify proteins. Philos Trans R Soc Lond B Biol Sci. 2012 Sep 19;367(1602):2513-6. doi: 10.1098/rstb.2012.0013. Review.

Wang Z, Shah OJ and Hunter T. 2012. The transcriptional coactivators p/CIP and SRC-1 control insulin resistance through IRS1 in obesity models. PLoS One. 2012;7(7):e36961. doi: 10.1371/journal.pone.0036961. Epub 2012 Jul 31.

Zheng X and Hunter T. 2013. Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism. Cell Res. 2013 Jul;23(7):886-97. doi: 10.1038/cr.2013.66. Epub 2013 May 14.

Ma, H., Han, B.K., Guaderrama, M., Aslanian, A., Yates III, J.R., Hunter, T., and Wittenberg, C. 2014. Psy2 targets PP4 to dephosphorylate Mth1 thereby antagonizing PKA to repress glucose transporter genes. Mol. Cell. Biol. 34:452-463.

Carrano AC, Dillin A and Hunter T. 2014. A Krüppel-like factor downstream of the E3 ligase WWP-1 mediates dietary-restriction-induced longevity in Caenorhabditis elegans. Nat Commun. May 8;5:3772. doi: 10.1038/ncomms4772.

Hunter T. 2014. The genesis of tyrosine phosphorylation. Cold Spring Harb Perspect Biol. May 1;6(5). pii: a020644. doi: 10.1101/cshperspect.a020644.

Ma L, Aslanian A, Sun H, Jin M, Shi Y, Yates JR 3rd and Hunter T. 2014. Identification of SUMO Substrates with Diverse Functions Using the Xenopus Egg Extract System. Mol Cell Proteomics. 2014 May 5.

Aslanian A, Yates JR 3rd and Hunter T. 2014. Mass spectrometry-based quantification of the cellular response to methyl methanesulfonate treatment in human cells. DNA Repair (Amst). 2014 Mar;15:29-38. doi: 10.1016/j.dnarep.2013.12.007. Epub 2014 Jan 22.

Zhang Y and Hunter T. 2014. Roles of Chk1 in cell biology and cancer therapy. Int J Cancer. 2014 Mar 1;134(5):1013-23. doi: 10.1002/ijc.28226. Epub 2013 May 28. Review.